A systematic and thorough method for identifying the significant links in biochemical pathways with high sensitivity.
FEvER software is freely available and is packaged as JAR file containing all the libraries used. It's very straight forward to use the software, assuming that Java Runtime Environment (JRE) is installed on your system. You can check if JRE is installed and running properly on your system by visiting the following test on Java homepage. Note that the page checks your system for the most current version available; as long as you have Java version 5+ running the FEvER software shouldn't be a problem.
Relase name Release Date Download file FEvER-0.6.2 - Rev.94 Mar 26, 2012 download FEvER-0.5.4 - Rev.73 Dec 16, 2011 download
Once you have confirmed that you have the required Java version installed and running properly on your system, you can run the software by double clicking on the JAR file and filling the parameters. Alternatively you can run the java -jar <jar_file> <parameter_file> command on a terminal/command prompt; where <jar_file> refers to the name of the JAR file you have downloaded and <parameter_file> refers to a text file which holds the parameters to be used by the software.
See example below:
> java -jar fever-0.5.4-r73.jar param.txt
Note that FEvER uses a significant amount of memory and processor power. It is important to keep in mind that if the dataset to be analyzed is rather large you will probably need to give extra memory to Java Virtual Machine. This is typically done with a command-line parameter, see example below where the JVM is given 2GB heap maximal heap space.
> java -Xmx2g -jar fever-0.5.4-r73.jar