Global linear regression normalization

Log2 transformed data is normalized by robust linear regression using the function "rlm" from the MASS package.

Usage

performGlobalRLRNormalization(rawMatrix, noLogTransform = FALSE)

Arguments

rawMatrix

Target matrix to be normalized

noLogTransform

Assumes no need for log transformation

Value

Normalized matrix

Examples

data(example_data_only_values_small)
normMatrix <- performGlobalRLRNormalization(example_data_only_values)